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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPA2
All Species:
6.36
Human Site:
Y120
Identified Species:
10
UniProt:
Q9H2U2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2U2
NP_001029363.1
334
37920
Y120
P
M
N
P
I
K
Q
Y
V
K
D
G
K
L
R
Chimpanzee
Pan troglodytes
XP_001164495
327
36742
Y128
N
L
F
P
Y
K
G
Y
I
W
N
Y
G
A
I
Rhesus Macaque
Macaca mulatta
XP_001082969
325
36595
Y120
P
L
N
P
I
K
Q
Y
V
K
D
G
K
L
R
Dog
Lupus familis
XP_535679
303
34598
D120
A
L
P
Q
T
W
E
D
P
H
R
K
D
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91VM9
330
38096
K120
K
Q
D
I
K
N
G
K
L
R
Y
T
P
N
I
Rat
Rattus norvegicus
NP_001129343
330
37824
R122
D
T
K
N
G
R
L
R
Y
T
P
N
I
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420502
467
51453
D250
P
L
N
P
I
K
Q
D
T
K
K
G
K
P
R
Frog
Xenopus laevis
NP_001084935
304
34676
D120
A
L
P
Q
T
W
E
D
P
K
H
I
D
N
D
Zebra Danio
Brachydanio rerio
NP_001017833
291
32624
K108
T
W
E
D
P
G
H
K
D
N
D
T
G
C
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77460
338
37921
D122
P
M
N
P
I
K
Q
D
I
K
K
G
K
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18680
407
44134
D195
P
F
S
P
I
K
Q
D
E
K
K
G
V
A
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O48556
214
24351
R31
I
L
S
S
L
S
R
R
S
V
A
A
H
P
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXC9
300
33362
A117
E
I
P
K
E
S
K
A
K
M
E
V
A
T
D
Baker's Yeast
Sacchar. cerevisiae
P00817
287
32281
P104
F
P
Q
T
W
E
D
P
N
V
S
H
P
E
T
Red Bread Mold
Neurospora crassa
Q6MVH7
290
32621
N107
P
Q
T
W
E
D
P
N
S
I
H
P
E
T
K
Conservation
Percent
Protein Identity:
100
50.9
91.3
78.1
N.A.
75.4
73.6
N.A.
N.A.
47.5
57.1
54.4
N.A.
45.2
N.A.
38.3
N.A.
Protein Similarity:
100
67
92.8
84.7
N.A.
84.1
83.5
N.A.
N.A.
56.9
72.1
67.9
N.A.
60.9
N.A.
52.8
N.A.
P-Site Identity:
100
20
93.3
0
N.A.
0
0
N.A.
N.A.
66.6
6.6
6.6
N.A.
80
N.A.
53.3
N.A.
P-Site Similarity:
100
40
100
13.3
N.A.
20
6.6
N.A.
N.A.
73.3
20
6.6
N.A.
86.6
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
23.3
N.A.
34.4
44.6
42.2
Protein Similarity:
N.A.
40.4
N.A.
50
58.3
58
P-Site Identity:
N.A.
0
N.A.
0
0
6.6
P-Site Similarity:
N.A.
26.6
N.A.
20
6.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
0
0
0
7
0
0
7
7
7
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% C
% Asp:
7
0
7
7
0
7
7
34
7
0
20
0
14
0
14
% D
% Glu:
7
0
7
0
14
7
14
0
7
0
7
0
7
7
0
% E
% Phe:
7
7
7
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
0
0
7
7
14
0
0
0
0
34
14
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
7
14
7
7
0
0
% H
% Ile:
7
7
0
7
34
0
0
0
14
7
0
7
7
0
14
% I
% Lys:
7
0
7
7
7
40
7
14
7
40
20
7
27
7
7
% K
% Leu:
0
40
0
0
7
0
7
0
7
0
0
0
0
20
0
% L
% Met:
0
14
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
7
0
27
7
0
7
0
7
7
7
7
7
0
14
0
% N
% Pro:
40
7
20
40
7
0
7
7
14
0
7
7
14
14
7
% P
% Gln:
0
14
7
14
0
0
34
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
7
14
0
7
7
0
0
0
34
% R
% Ser:
0
0
14
7
0
14
0
0
14
0
7
0
0
0
7
% S
% Thr:
7
7
7
7
14
0
0
0
7
7
0
14
0
14
7
% T
% Val:
0
0
0
0
0
0
0
0
14
14
0
7
7
0
0
% V
% Trp:
0
7
0
7
7
14
0
0
0
7
0
0
0
0
7
% W
% Tyr:
0
0
0
0
7
0
0
20
7
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _